Biology 112
General
Biology I
Spring 2008
Course Syllabus
Instructor: Dr. Donald Glassman
Office: Rm. 10D, Bldg. 4
Phone: 515-964-6237
E-mail: dlglassman@dmacc.edu
Office Hours: Monday/Wednesday 9:00-10:00 & 12:15 - 1:15,
Friday 9:00-10:00
Text: Biology. 7th edition. Neil
A. Campbell.
Lab Manual: Biology Laboratory Manual Vodopich/Moore (Custom
edition for DMACC)
Course
Description: This
course is designed for biology/science majors. It is a rigorous introductory
course. Its mission is to provide the student with a solid framework for
further coursework. Topics of emphasis will include: the chemistry of living
things, cells, genetics, evolution, viruses, bacteria and protists.
I. Lecture A tentative lecture schedule is attached. You are responsible
for all material in the assigned chapters as well as the material presented in
class. If you must miss a lecture it is your responsibility to obtain
the notes from a classmate. Attendance and attention in lecture is vital to your success.
II. Lab You are required to attend each lab. You can receive no points for a lab that you did not
attend! A laboratory schedule is attached. You should be adequately prepared
for each laboratory period, this includes reading the
laboratory exercise before the
laboratory period.
III. Safety Laboratory safety is of paramount importance. It is essential
that you follow proper procedures at all times. No food, drink, tobacco or gum can be permitted in the lab. There
is zero tolerance for inappropriate activities in the laboratory.
IV. Web Site http://www.dmacc.cc.ia.us/instructors/dlglassman/
The pertinent course information is also posted on
my faculty web site. This site may be used throughout the semester to post
information and assignments. You can also use this site as a link to other
science oriented Web sites of interest.
V. Grading There
will be four (4) written exams (100 points each) and a comprehensive final (200
points). The laboratory performance will be evaluated by participation, lab
reports and quizzes (specifics will be announced). A comprehensive practical
will be given (100 points). You must pass both the lecture and
laboratory components of the course to pass the course!!
Grades will be assigned based on the percentage of
total points possible you earn:
A 90-100
B 80-89
C 70-79
D 60-69
F <60
Tentative Point Totals
Lecture Exams 400
Final 200
General
attendance, attitude, and participation ~ 25
Laboratory Attendance/Reports/Quizzes/Handouts
~140
Practical 100
Total Points
~865
I.
Policy on Missed Exams,
Quizzes, and Labs: NO makeup labs or quizzes will
be given. One and only one missed exam may be made up by adding
the appropriate number of points missed (100) to the value of the final exam.
Example: If one unit test is missed, the final for that person will be worth
200 pts (value of final) + 100 pts (value of missed exam) = 300 pts.
II. Competencies: The attached competencies
are the minimum skills and knowledge that you must master to complete this
course. They do not reflect the degree of knowledge and understanding you must
demonstrate to earn a passing grade. If you have any questions concerning
course content or expectations do not hesitate to raise them.
VII. Suggestions for success: There are many avenues for success in this
class, but
they all involve a commitment of
time and effort which may be greater than that
expected of you in a non-science
class. Plan extra time for this class. Your
attendance in all classes is very
important; few students will have success in this
class with a casual attendance
ethic. Not everyone assimilates information in the
same manner, try to vary your
methods of study…work in a group, make charts
and tables, quiz yourself,
study out-loud and/or utilize the CD-ROM packaged
with your text. Don't get behind
and if you are having trouble, seek help early.
There is no
substitute for effort!
Biology 112 Laboratory Schedule
Spring 2008
TENTATIVE
Week Thursday LAB
2 (1/17) Exercise
#2 Measurements in Biology
3 (1/24) Exercise
#3 The Microscope
4 (1/31) Exercise #6 Biologically Important Molecules
5 (2/7) Exercise #4 The Cell
6 (2/14) Exercise #9 Diffusion and Osmosis
7 (2/21) Exercise #13 Photosynthesis
8 (2/28) Exercise
#14 Mitosis
9 (3/6) Exercise
#17 Genetics
10 (3/13) DNA isolation from E. coli (handout)
11 (3/20) Spring Break !!!!!!!!!
12 (3/27) Exercise #18 Evolution
13 (4/3) Exercise #24 Survey of Bacteria
14 (4/10) Exercise #25 Survey of Algae
15 (4/17) Exercise #26 Survey of Protozoa and Slime molds
16 (4/24) Lab Practical
Biology
112
Tentative Lecture
Schedule Spring 2008
1 1/7 Exploring Life (1)
The Chemical Context of Life (2)
Water and Fitness of the Environment (3)
The Structure and Function of Macromolecules (5)
3 1/21 No class Monday January 21st
An Introduction to Metabolism (8)
4 1/28 Chapter 8 continued
Exam 1 Wednesday
A Tour of the Cell (6)
5 2/4 Chapter 7 continued
Membrane Structure and Function (7)
6 2/11 Cellular Respiration:Harvesting Chemical Energy (9)
Photosynthesis (10)
7 2/18 Chapter 10 continued
Exam 2 Friday
8 2/25 The Cell Cycle (12)
Meiosis and Sexual Life Cycles (13)
9 3/3 Mendel and the Gene Idea (14)
The Chromosomal Basis of Inheritance (15)
10 3/10 The Molecular Basis of Inheritance (16)
Exam 3 Wednesday
11 3/17 Spring Break
12 3/24 From Gene to Protein (17)
13 3/31 The Genetics of Viruses and Bacteria (18)
Genome Organization and Expression in Eucaryotes (19)
DNA technology (20)
14 4/7 Exam 4 Monday
Descent with Modification: A Darwinian View of Life (22)
The Evolution of Populations (23)
15 4/14 The Origins of Species (24)
Phylogeny and Systematics (25)
16 4/21 Origin of Life (26)
Prokaryotes Diversity (27)
Protists (28)
FINALS FINAL EXAM (Comprehensive- 200 points)
Section
A Monday
4/28/2007 10:30-12:45
Section
B Wednesday
4/30/2007 12:00 - 2:15
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Disclaimer
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“This syllabus is representative of materials that will be
covered in this class; it is not a contract between the student and the
institution. It is subject to change
without notice. Any potential
exceptions to stated policies and requirements will be addressed on an
individual basis, and only for reasons that meet specific requirements. If you have any problems related to this
class, please feel free to discuss them with me.” |
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Nondiscrimination
Policy
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Students who wish
additional information or assistance may contact the Executive Dean, Student Services, Laurie Wolf, Building 1,
515-964-6437 or the EEO/AA Officer,
Dr. Sandy Tryon, Human Resources, Bldg. 1, 515-964-6301 or they may refer
to Student Services procedure 4645 located on the DMACC Intranet at http://my.dmacc.edu/procs.aspx.
Go to Policies & Procedures and
choose Student Services Procedures. Employees and applicants who wish
additional information or assistance may contact the EEO/AA Officer, Dr. Sandy Tryon, Human Resources, Bldg. 1,
515-964-6301 or refer to HR Procedures 3000, 3005, 3010, 3015, and 3020 at http://www.dmacc.edu/hr/hrpp.asp
. For requests for
accommodations, the Accommodation/Section
504/ADA Coordinator, Sharon Bittner, can be contacted at
515-964-6857. Students with requests
for accommodations should refer to the Student Services procedure 4610
located on the DMACC Intranet at http://my.dmacc.edu/default.aspx . Go to Policies & Procedures and choose
Student Services Procedures. |
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Academic Misconduct
Academic Integrity, based on
the values of honesty, trust, fairness, respect, and responsibility, is a
fundamental principle of scholarship at DMACC. DMACC’s
Academic Misconduct Policy prohibits: plagiarism (using another person’s
writing or copying any work without proper citation), falsification,
unauthorized collaboration during a test or on an assignment, or substitution
for another student to take an exam, course or test.
If you are to
benefit from this class and be properly evaluated for your contributions, it is
important for you to be familiar with and follow DMACC’s
Academic Misconduct policy. Students are encouraged to review DMACC’s Academic Misconduct Policy on-line at http://www.dmacc.edu/handbook/polprocedures/es4670.pdf
or in the DMACC Student Handbook.
Work that
violates these values is incompatible with the goals of this class and will not be
tolerated. Students who are found responsible for a violation of the
Academic Misconduct Policy will receive a failing grade for the course.
Students have the right to appeal and may do so by following the procedures
described in the Academic Misconduct policy.
COURSE
COMPETENCIES:
During this course, the
student will be expected to:
1. Use the scientific method.
1.1 Explain how use of the scientific method brought about
the current understanding of the structure and functions of living organisms.
1.2 Describe contributions of significant researchers in
biology.
1.3 Describe how methods used by researchers in biology
enables them to make major contributions to the field.
2. Describe characteristics of life and the study of
biology.
2.1 Characterize organisms.
2.2 Classify organisms.
2.3 Name organisms.
3. Summarize the characteristics of life molecules.
3.1 Use chemical terminology.
3.2 Describe atoms, molecules, chemical bonds, and chemical
reactions.
3.3 Describe characteristics of water.
3.4 Use the pH scale.
3.5 Summarize basics of carbon chemistry.
3.6 Identify functional groups of organic molecules.
3.7 Identify characteristics of carbohydrates, lipids,
proteins, and nucleic acids.
3.8 Identify amino acids.
3.9 Identify levels of protein structure.
3.10 Identify characteristics of nucleic acids.
3.11 Investigate biological molecule in the laboratory.
4. Summarize metabolism.
4.1 Use terminology of metabolism.
4.2 Characterize metabolic pathways.
4.3 Classify forms of energy.
4.4 Explain the laws of thermodynamics.
4.5 Apply concepts of free-energy.
4.6 Describe cellular work.
4.7 Summarize ways ATP serves as the energy currency of
life.
4.8 Characterize enzymes.
4.9 Relate energy of activation to enzyme activity.
4.10 Describe enzyme function and regulation.
4.11 Describe control of metabolism.
4.12 Investigate enzymes in the laboratory.
5. Summarize microscopy.
5.1 Use terminology of microscopy.
5.2 Use a light microscope.
5.3 Describe electron microscopes and their use.
6. Summarize characteristics of cells.
6.1 Use current terminology to describe cells and cellular
constituents.
6.2 Distinguish between prokaryotic and eukaryotic cells.
6.3 Describe features and functions of the nucleus and its
contents.
6.4 Describe ribosomes and their
function.
6.5 Describe features and functions of the endomembrane system of cells.
6.6 Describe functions of cell vesicles and vacuoles.
6.7 Explain how the structures of the mitochondrion and the
chloroplast relate to their functions.
6.8 Distinguish between plastids of plant cells.
6.9 Describe features and functions of the cytoskeleton.
6.10 Explain how the structures of cilia and flagella
provide for their functions.
6.11 Describe development and structure of plant cell
walls.
6.12 Explain how the glycocalyx
of animal cells provides for cellular functions.
6.13 Differentiate between types of intercellular
junctions.
6.14 Identify cellular components in the laboratory.
7. Summarize cell membrane structure and function.
7.1 Use current terminology to describe cell membranes and
membrane transport.
7.2 Summarize functions of the cell membrane.
7.3 Explain how membrane composition determines membrane
fluidity and structure.
7.4 Classify transport proteins.
7.5 Describe diffusion and its relation to potential
energy.
7.6 Explain osmosis.
7.7 Explain the generation of membrane potential.
7.8 Describe endocytosis.
7.9 Investigate membrane transport in the laboratory.
8. Summarize cellular respiration.
8.1 Use current terminology to describe harvest of chemical
energy in cells.
8.2 Diagram energy flow through the biosphere.
8.3 Summarize chemical reactions of cellular respiration of
glucose.
8.4 Distinguish between substrate-level and oxidative phosphorylation.
8.5 Distinguish between oxidation and reduction.
8.6 Name coenzymes used in cellular respiration.
8.7 Specify the cellular sites of the processes of cellular
respiration.
8.8 Explain chemosmotic phosphorylation.
8.9 Describe fermentation and why it is necessary.
8.10 Relate how cells get energy from glucose to how they
get energy from other molecules.
8.11 Explain how ATP production is controlled in cells.
8.12 Explain the evolutionary significance of glycolysis.
8.13 Investigate respiration in the laboratory.
9. Summarize photosynthesis.
9.1 Use current terminology to describe photosynthetic
events and structures.
9.2 Distinguish between autotrophic and heterotrophic
nutrition.
9.3 Distinguish between photosynthetic autotrophs
and chemosynthetic autotrophs.
9.4 Relate chloroplast structure to function.
9.5 Summarize chemical reactions of photosynthesis.
9.6 Describe features of light.
9.7 Relate the absorption spectrum of chlorophyll to its
action spectrum.
9.8 Explain of light absorption cause the electron flow of photosystems I and II.
9.9 Compare cyclic and noncyclic
electron flow in the light reactions of photosynthesis.
9.10 Describe the roles of ATP and NADPH in the
Calvin-Benson cycle.
9.11 Describe photorespiration.
9.12 Describe evolutionary adaptations that minimize
photorespiration.
9.13 Describe the chemical fates of the products of
photosynthesis.
9.14 Investigate photosynthesis in the laboratory.
10. Summarize cellular reproduction.
10.1 Use current terminology to describe cellular
reproduction.
10.2 Describe binary fission in prokaroyes.
10.3 Describe chromosomes and their structural forms.
10.4 Summarize cell chromosome number changes in the sexual
life cycles.
10.5 Describe events of the periods of the cell cycle.
10.6 Identify characteristics and events of the phases of
mitosis.
10.7 Describe structures and events required for
chromosomal movement in mitosis.
10.8 Compare cytokinesis of plant
and animal cells.
10.9 Describe control of the cell cycle and the
consequences of lack of this control.
10.10 Explain the relationship of chromosomes to heredity.
10.11 Distinguish between sexual and asexual reproduction
of organisms.
10.12 Identify characteristics and events of the phases of
meiosis.
10.13 Differentiate between mitosis and meiosis.
10.14 Distinguish between mitotic interphase
and meiotic interkinesis.
10.15 Explain how independent assortment, crossing over,
and random fertilization contribute to genetic variability in sexually
reproducing organisms.
10.16 Explain how genetic variation in populations of
organisms is crucial to
10.17 Identify stages of mitosis and meiosis in the
laboratory.
11. Summarize Mendelian genetics.
11.1 Use current terminology of Medelian
genetics.
11.2 Summarize Mendel's laws of segregation and independent
assortment.
11.3 Use Punnett squares and the
laws of probability to predict the genotype and phenotype ratios of F1 and F2
generations of mono-, di-, and tri-hybrid crosses.
11.4 Differentiate between complete dominance, recessiveness, incomplete dominance, and codominance.
11.5 Explain how sex-linkage may affect genotype and
phenotype ratios.
11.6 Use pedigrees to determine patterns of inheritance.
11.7 Explain the presence of lethal genes in the
population.
11.8 Explain methods used in genetic screening.
11.9 Relate chromosomal inheritance to independent
assortment and sex determination.
11.10 Describe processes and results of crossing-over.
11.11 Describe how changes in chromosome number can occur
and the results of these changes.
11.12 Explain the theory of genomic imprinting.
11.13 Explain examples of extra nuclear inheritance.
11.14 Perform mendelian
crosses in the laboratory.
12. Summarize molecular genetics.
12.1 Describe the processes used to determine that DNA is
the genetic material.
12.2 Identify chemical characteristics of DNA replication.
12.3 Identify characteristics of DNA replication.
12.4 Explain the one gene-one polypeptide hypothesis.
12.5 Differentiate between RNA and DNA.
12.6 Differentiate between types of RNA.
12.7 Distinguish between transcription and translation by
processes and the location of these processes in cells.
12.8 Use the universal genetic code to work problems
involving transcription and translation.
12.9 Describe characteristics of the genetic code.
12.10 Explain the processes and cellular structures that
are involved in translation.
12.11 Explain processes involved translation in the
cytoplasm and on the rough endoplasmic reticulum.
12.12 Explain how protein targeting in cells. relates to the site of translation.
12.13 Describe differences between prokaryotic and eukaryotic
mRNA.
12.14 Explain eykaryotic mRNA
nuclear processing.
12.15 Describe functions of introns
and gene splicing.
12.16 Differentiate between types of base-sequence
mutations and their effects.
12.17 Investigate molecular genetics in the laboratory.
13. Summarize viral and bacterial genetics.
13.1 Summarize viral composition and function.
13.2 Describe processes of viral genome replication.
13.3 Distinguish between lytic
and lysogenic reproductive cycles in a bacteriophage.
13.4 Describe cellular processes used to defend against
viral infection.
13.5 Describe how viruses may cause cancers.
13.6 Describe means of virus transmission.
13.7 Relate hypotheses explaining viral evolution.
13.8 Differentiate between viruses and living organisms.
13.9 Describe the bacterial chromosome and binary fission.
13.10 Describe bacterial genetic recombination.
13.11 Describe roles of plasmids in bacterial life.
13.12 Describe natural and laboratory bacterial
transformation and transduction.
13.13 Explain how operons
function in metabolic control.
14. Summarize genome organization and expression in
eukaryotes.
14.1 Compare genomic organization in eukaryotes to
prokaryotes.
14.2 Describe DNA packing.
14.3 Distinguish between types of chromatin and the functions.
14.4 Describe hypothesized functions and origins or
repetitive sequences and multigene families.
14.5 Describe examples of genome plasticity.
14.6 Describe the molecular basis of gene expression
control.
15. Summarize the processes, applications, and ethics of
genetic engineering.
15.1 Describe functions and uses of restriction enzymes.
15.2 Describe uses of gel electrophoresis in DNA
technology.
15.3 Describe vectors used in recombinant DNA technology.
15.4 Describe source of genes for cloning.
15.5 Outline procedures used for gene cloning and
transformation of bacteria and other cells.
15.6 Outline procedures used to sequence DNA.
15.7 Describe applications of recombinant DNA technology.
15.8 Describe procedures and processes that comprise the
Human Genome project.
15.9 Discuss safety and ethical considerations of
recombinant DNA research.
16. Summarize elements of evolution.
16.1 Describe development of evolutionary theory.
16.2 Summarize the Hardy-Weinberg theorem.
16.3 Use terminology of evolution.
16.4 Apply knowledge of molecular genetics to evolutionary
theory.
16.5 Relate sexual dimorphism and diploidy
to evolution.
16.6 Summarize speciation.
16.7 Outline phylogeny.
16.8 Describe views of the origin of life.
16.9 Investigate evolution in the laboratory.
17. Examine the prokaryotes.
17.1 Use appropriate terminology to describe prokaryotes.
17.2 Classify prokaryotes.
17.3 Describe prokaryotic metabolism, motility, gene
exchange, and survival mechanisms.
17.4 Describe prokaryotic interactions with ecosystems.
17.5 Describe factor that allow prokaryotes to cause
disease.
17.6 List Koch's postulates.
17.7 Classify toxins.
17.8 Observe prokaryotes in the laboratory.
18. Examine the protists.
18.1 Point out the major groups of protists.
18.2 Compare the major groups of protists.
18.3 Explain protoplasmic level of development.
18.4 Discuss principles of parasitism.
18.5 Describe life cycles and pathology of parasitic protozoans.
18.6 Point out the economic importance of the protozoans.
18.7 Observe protists in the laboratory.