Biology 187

General Microbiology

 

Spring 2008

Course Syllabus

 

Instructor:         Dr. Donald Glassman

 

Office: Rm 10D, Building 4

Phone:              515-964-6237

E-Mail: dlglassman@dmacc.edu

Web site:          http://www.dmacc.cc.ia.us/instructors/dlglassman/

Office Hours:    Monday/Wednesday 9:00-10:00 & 12:15 - 1:15, Friday 9:00-10:00

 

 

Text:                 Brock Biology of Microorganisms .  11th edition   Madigan/Martinko/Parker 2006

Lab Manual:     Laboratory Experiments in Microbiology.  8th edition.  Johnson & Case.  2007

 

 

I.  Lecture       A tentative lecture schedule is attached.  You are responsible for all material in the assigned chapters as well as the material presented in class.  If you must miss a lecture it is your responsibility to obtain the notes from a classmate.  Attendance in lecture is vital to your success.

 

II.  Lab            You are required to attend each lab.  A completed lab report for the previous lab session is due at the beginning of the next lab session.  Late lab reports can receive a maximum of 50% of their value.  You can receive no points for a lab that you did not attend!

 

III. Safety       Laboratory safety is of paramount importance.  It is essential that you follow proper procedures at all times.  Some of the microorganisms you will be handling are pathogenic!  No food, drink, tobacco or gum can be permitted in the lab.  A lab coat or smock must be worn during lab sessions.  Safety glasses or goggles must be worn when working with live cultures.  Read and commit to memory the material in the handout “Microbiology Laboratory Rules and Recommendations.”

 

IV. Web Site               http://www.dmacc.cc.ia.us/instructors/dlglassman/

The pertinent course information is also posted on my faculty web site. This site may be used throughout the semester to post information and assignments. You can also use this site as a link to other science oriented Web sites of  interest.

 

V. Policy on Missed Exams, Quizzes, and Labs:    

NO makeup labs or quizzes will be given. One missed exam may be made up by adding the appropriate number of points missed to the value of the final exam.  Example:  If one unit test is missed, the final for that person will be worth 200 pts (value of final) + 100 pts (value of missed exam) = 300 pts.

 

VI. Competencies:    

The attached competencies are the minimum skills and knowledge that you must master to complete this course. They do not reflect the degree of knowledge and understanding you must demonstrate to earn a passing grade. If you have any questions concerning course content or expectations do not hesitate to raise them.

 

VII. Grading   There will be three (3) written exams (100 points each) and a comprehensive final (200 points).  Lab reports are worth 10 points each if turned in on time and complete.  Lab exercise 8 requires identification of a morphologic unknown.  This lab is worth 20 points.  The lab report for the bacterial unknown is worth 50 points.  A comprehensive practical will be given (100 points).  Quizzes and special assignments will also be given.  You must pass both the lecture and laboratory components of the course to pass the course.

Final grades will be assigned based on percentage of total points possible you earn:

 

                                    A         90-100

                                    B          80-89

                                    C         70-79

                                    D         60-69

                                    F          <60

 

 

Tentative point totals

Lecture Exams                                                  300

                        Final                                                                             200

                        Lab Reports                                                               ~180

                        Morphologic Unknown                                       20

                        Bacterial Unknown                                                         50

                        Practical                                                                       100

                        Attendance, attitude, conduct and participation  ~25

Special Assignments                                                     ~20

                        Total Points                                        ~895

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Biology 187

Very Tentative Lecture Schedule

Spring 2008

 

Week                     Date                        Topic                                                                                                                                     

1                              1/7                           Chapters 1 & 2  Overview of Microbiology

1/9                           Chapter 3 – Macromolecules

 

2                              1/14                         Chapter 4 –Cell Structure and Function

1/16                         Chapter 4 (cont.)

 

3                              1/21                        No Class –  School Holiday

1/23                         Chapter 5 – Nutrition and metabolism

                                                               

4                              1/28                         Chapter 5 (cont.)

                                1/30                         Chapter 6 – Microbial Growth

 

5                              2/4                           EXAM I

                2/6                           Chapter 7 – Microbial Molecular Biology

 

6                              2/11                         Chapter 7 (cont.)

                                2/13                         Chapter 8 – Regulation of Gene Expression

                                               

7                              2/18                         Chapter 10 – Microbial Genetics

                                2/20                         Chapter 10 (cont.)

 

8                              2/25                         Chapter 31 – Genetic Engineering and Biotechnology

                                2/27                         Chapter 9 - Viruses

                                                               

9                              3/3                           Chapter 9 (cont.)

                                3/5                           EXAM II

 

10                            3/10                         Chapter 12 – Bacteria

                                3/12                         Chapter 12 (cont.)

 

11                           3/17-3/21              Spring Break ……No Classes        

                               

12                            3/24                         Chapter 12 (cont.)

                                3/26                         Chapter 13 – Archaea

 

13                            3/31                         Chapter 14 - Eukaryotic microorganisms

                                4/2                           Chapter 14 (cont.)

 

14                            4/7                           EXAM III

                                4/9                           Chapters 18 & 19 Microbial Ecology

 

15                            4/14                         Chapter 18 & 19 (cont.)

                                4/16                         Chapter 20 – Microbial Growth Control

 

16                            4/21                         Chapter 20 (cont.)

                                4/23                         Chapter 22 – Immunology

 

17                            FINAL EXAM                       April 30th  (Wednesday) 2:30-4:45         

 

 

 

Biology 187 Laboratory Schedule

Spring 2008

DATE                  LAB                                                                              

TU       1-8                   Laboratory Orientation and Safety pp. 1-4

Ex. 1 Use & Care of the Microscope

               

TH       1-10                 Ex. 2-   Examination of Living Organisms

 

TU       1-15                 Ex. 3-   Preparation of Smears & Simple Staining

                                   

TH       1-17                 Ex. 4-   Negative Staining

                                    Ex. 5-   Gram Staining

 

TU       1-22                 Ex. 6-   Acid-Fast Staining

                                    Ex. 7-   Structural Stains (Endospore, Capsule, & Flagella)

 

TH       1-24                 Ex. 8-   Morphologic Unknown

                                    Ex. 26 - Effectiveness of Handscrubbing

 

TU       1-29                 Evaluate Ex 26

Ex. 9-   Microbes in the Environment

                                    Ex. 10- Transfer of Bacteria: Aseptic Technique

 

TH       1/31                 Evaluate Ex. 9 and 10

                                   

 

TU       2-5                   Ex 11-  Isolation of Bacteria by Dilution Techniques

                                    Ex. 12- Special Media for Isolating Bacteria

 

TH       2-7                   Evaluate Ex. 11 and 12

                                   

 

TU       2-12                      Ex. 13- Carbohydrate Catabolism

                                    Ex. 14- Fermentation of Carbohydrates

 

 

TH       2-14                 Evaluate Ex. 13 and Ex. 14

 

TU       2-19                 Ex. 15 Protein Catabolism, Part 1

                                    Ex. 16 Protein Catabolism, Part 2

 

TH       2-21                 Evaluate 15 & 16

 

TU       2-26                 Ex. 17 Respiration

                                    Ex. 18 Rapid Identification Methods

 

TH       2/28                 Evaluate 17 and 18

           

TU       3-4                   Identification of Unknown Microorganism - Handout

 

TH       3-6                   Unknowns - continued

 

TU       3-11                 Unknowns – conclusion

                                    Ex. 19 Oxygen and the growth of Bacteria

 

TH      3-13                  Evaluate Ex. 19

                                    Ex. 43- Blood Group Determination: Slide Agglutination

 

March 17  - March 21           SPRING BREAK!!!

 

                                   

TU       3-25                 Ex. 24- Chemical Methods of Control: Antimicrobial Drugs

                                    Ex. 25- Chemical Methods of Control: Disinfectants & Antiseptics

 

TH       3-27                 Evaluate 24 and 25

 

 

TU       4-1                   Virology Lab - Handout

                                   

 

TH       4-3                   Evaluate Virology Lab

                                    Ex. 36 Phototrophs

 

TU       4-8                   Ex. 52- Microbes in Water: Multiple Tube Analysis

                                    Ex. 54 - Microbes in Food: Contamination

 

TH       4-10                 Evaluate 52 and 54

                                    Ex. 57- Microbes in Soil: Bioremediation

 

TU       4-15                 Evaluate 57

                                    Bacterial Transformation (pGLO) - Handout

 

TH       4-17                 Evaluate Bacterial Transformation lab

                                    DNA Restriction analysis - Handout

 

TU       4-22                 Evaluate DNA Restriction analysis

                                    Lab Cleanup/Review

 

TH       4-24                 PRACTICAL EXAM

 

 

 

DMACC Information Web Sites

DMACC home page

http://www.dmacc.edu/

Instructor home pages

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Admissions & registration

http://www.dmacc.edu/potienti.asp

Cellular phone use statement

http://www.dmacc.edu/student_services/cellphone.asp

WebCT

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Student handbook

http://www.dmacc.edu/handbook/welcome.asp

Add/drop dates

http://www.dmacc.edu/registration/add_drop.asp

Refund policy

http://www.dmacc.edu/refund.asp

Support Services

Accommodations

“It is the policy of DMACC to accommodate students with disabilities.  Any student with a documented disability who requires reasonable accommodation should contact the special needs coordinator at 515-964-6850 voice or 515-964-6810 TTY.”

Services for students with disabilities

http://www.dmacc.edu/student_services/disabilities.asp  

 

Contact the special needs coordinator at 515-964-6850V,
515-964-6809 TTY or the counseling & advising office on any campus for an Application for Accommodation.

Academic & educational advising

http://www.dmacc.edu/advising/welcome.asp

Career counseling

http://www.dmacc.edu/counseling/

Library

http://www.library.dmacc.edu/

 

Building 6, room 3

Monday – Thursday 7:30 am to 9:00 pm

Friday – 7:30 am to 4:00 pm

Saturday – 8:00 am to 1:00 pm

Academic Achievement Center

http://www.dmacc.edu/student_services/academic_achievement_center.asp

 

Provides academic assistance for students on a drop-in basis.  Also serves as a make-up testing center.

 

515-964-6558 or 1-800-362-2127 ext. 6558

 

Building 6, Room 20

Monday – Thursday 8:00 am to 7:00 pm

Friday – 8:00 am to 2:30 pm

NOTE:  Summer hours may vary

Computer labs

http://www.dmacc.edu/helpdesk/pc_labs.htm

 

Building 6

Monday – Thursday 7:30 am to 10:00 pm

Friday – 7:30 am to 4:00 pm

Saturday – 7:30 am to 1:00 pm

Disclaimer

“This syllabus is representative of materials that will be covered in this class; it is not a contract between the student and the institution.  It is subject to change without notice.  Any potential exceptions to stated policies and requirements will be addressed on an individual basis, and only for reasons that meet specific requirements.  If you have any problems related to this class, please feel free to discuss them with me.”

Nondiscrimination Policy

Des Moines Area Community College shall not engage in or allow discrimination covered by law.  This includes harassment based on race, color, national origin, creed, religion, gender, sexual orientation, age, and disability.  Veteran status in educational programs, activities, employment practices, or admission procedures is also included to the extent covered by law.  Individuals who believe they have been discriminated against may file a complaint through the College Discrimination Complaint Procedures.  Complaint forms may be obtained from the DMACC Web site, the Ombudsperson, Judicial Officer, Human Resources Department, the campus Provost's Offices, and Academic Deans’ Offices.

 

Students who wish additional information or assistance may contact the Executive Dean, Student Services, Laurie Wolf, Building 1, 515-964-6437 or the EEO/AA Officer, Dr. Sandy Tryon, Human Resources, Bldg. 1, 515-964-6301 or they may refer to Student Services procedure 4645 located on the DMACC Intranet at http://my.dmacc.edu/procs.aspx.  Go to Policies & Procedures and choose Student Services Procedures. Employees and applicants who wish additional information or assistance may contact the EEO/AA Officer, Dr. Sandy Tryon, Human Resources, Bldg. 1, 515-964-6301 or refer to HR Procedures 3000, 3005, 3010, 3015, and 3020 at http://www.dmacc.edu/hr/hrpp.asp .

 

For requests for accommodations, the Accommodation/Section 504/ADA Coordinator, Sharon Bittner, can be contacted at 515-964-6857.  Students with requests for accommodations should refer to the Student Services procedure 4610 located on the DMACC Intranet at http://my.dmacc.edu/default.aspx .  Go to Policies & Procedures and choose Student Services Procedures.

 

Academic Misconduct

 

Academic Integrity, based on the values of honesty, trust, fairness, respect, and responsibility, is a fundamental principle of scholarship at DMACC. DMACC’s Academic Misconduct Policy prohibits: plagiarism (using another person’s writing or copying any work without proper citation), falsification, unauthorized collaboration during a test or on an assignment, or substitution for another student to take an exam, course or test.

 

If you are to benefit from this class and be properly evaluated for your contributions, it is important for you to be familiar with and follow DMACC’s Academic Misconduct policy. Students are encouraged to review DMACC’s Academic Misconduct Policy on-line at http://www.dmacc.edu/handbook/polprocedures/es4670.pdf or in the DMACC Student Handbook.

 

Work that violates these values is incompatible with the goals of this class and will not be tolerated. Students who are found responsible for a violation of the Academic Misconduct Policy will receive a failing grade for the course. Students have the right to appeal and may do so by following the procedures described in the Academic Misconduct policy.


COURSE COMPETENCIES:

During this course, the student will be expected to:

1. Identify the locations of safety equipment in the laboratory.

 

2. Explain the safety procedures and health rules of the microbiology laboratory.

 

3. Comply with safety and health rules of the biology laboratory.

3.1 Observe appropriate safety procedures for the microbiology laboratory.

3.2 Adhere to accepted health rules for the microbiology laboratory.

 

4. Demonstrate an understanding of the use of laboratory microscopes.

4.1 Identify the major parts of the microscope.

4.2 Demonstrate proper technique in the use of a microscope.

4.3 Demonstrate proper care of a microscope.

 

5. Relate microbial morphology to function.

 

6. Classify disease causing microorganisms.

 

7. Differentiate between Gram-negative and Gram-positive bacteria

 

8. Identify structures and functions of endospores and plasmids.

 

9. Characterize microbial metabolism and growth.

9.1 Summarize basic concepts of life chemistry.

9.2 Relate cellular functions.

9.3 Discuss cellular respiration.

9.4 Differentiate among the metabolic reactions of different

9.5 Identify nutrient needs of disease-causing bacteria.

 

10. Relate microbial characteristics to their disease-causing capabilities.

10.1 Relate Koch's postulates to modern concepts of disease.

10.2 Explain terminology describing disease processes.

10.3 Discuss infection.

 

11. Examine epidemiology.

 

12. Describe the normal flora of the human body.

 

13. Differentiate among selected disease-causing pathogens.

 

14. Identify methods of sterilization and disinfection.

 

15. Identify anti-pathogenic chemotherapeutic agents.

 

16. Explain the concept of host defense mechanisms.

16.1 Identify the factors that are important in disease resistance.

16.2 Differentiate between cell types involved in immunity.

16.3 Specify the characteristics of antibodies.

16.4 Differentiate between active and passive immunity.

 

17. Utilize antiseptic techniques.

 

18. Demonstrate an understanding of microbiology.

 

18.1 Demonstrate proper gram staining.

18.2 Prepare a bacteria culture.

 

19. Employ proper handwashing techniques.

20. Evaluate lab results.

21. Identify an unknown bacteria.

                22. Discuss the importance of environmental and industrial microbiology.